Description

Upajak 15mg Tablet (Upadacitinib) Uses, Side Effects, Dosage & Price in Pakistan

Upajak 15mg Tablet (Upadacitinib) is an extended-release prescription medicine that belongs to a group of medicines called Janus kinase (JAK) inhibitors. It works by reducing specific signals involved in inflammation and immune-system activity.

Upajak contains 15mg of upadacitinib and is used for certain inflammatory conditions, including rheumatoid arthritis and psoriatic arthritis, according to the product information. Because upadacitinib can increase the risk of serious infections and other complications, it should be taken only under the supervision of a qualified healthcare professional.

What Is Upajak 15mg Tablet?

Upajak 15mg Tablet contains upadacitinib as its active ingredient. It is an extended-release tablet designed for oral use.

Upadacitinib is a selective Janus kinase (JAK) inhibitor. JAK enzymes help transmit signals involved in immune and inflammatory responses. By inhibiting these pathways, upadacitinib can reduce abnormal inflammation associated with certain immune-mediated diseases.

The official Upajak prescribing information states that each extended-release tablet contains 15mg of upadacitinib.

Upajak 15mg Uses

Upajak may be prescribed for certain inflammatory and autoimmune conditions.

The manufacturer’s prescribing information lists it for:

• Moderate to severe active rheumatoid arthritis in adults who have had an inadequate response or intolerance to one or more TNF blockers.
• Active psoriatic arthritis in adults and pediatric patients aged 2 years and older who have had an inadequate response or intolerance to one or more TNF blockers.

Upadacitinib is also used internationally for additional conditions depending on the country’s approved product labeling, including some forms of atopic dermatitis, axial spondyloarthritis, ulcerative colitis and Crohn’s disease. The approved indications can differ by product and country.

Therefore, Upajak should not be used for a condition simply because another upadacitinib product is approved for it. Your doctor should determine whether it is appropriate for your specific condition.

How Does Upadacitinib Work?

Upadacitinib works by inhibiting Janus kinase enzymes involved in immune-system signaling.

JAK enzymes help transmit signals from certain cytokines and growth factors inside cells. These signals can contribute to inflammation. By blocking JAK activity, upadacitinib reduces some of these inflammatory signals.

This action can help control inflammation and symptoms associated with certain immune-mediated diseases.

Upajak 15mg Tablet Dosage

The appropriate dose of upadacitinib depends on the condition being treated, age, kidney and liver function, other medicines and the patient’s overall health.

For several adult inflamUpajak 15mg Tabletmatory conditions, including rheumatoid arthritis and psoriatic arthritis, 15mg once daily is a commonly recommended dose in official product information.

For other conditions, different strengths or induction doses may be used. For example, ulcerative colitis and Crohn’s disease can require higher induction doses before maintenance treatment.

Do not change the prescribed dose yourself. Your healthcare professional should select the appropriate dose and determine how long treatment should continue.

How to Take Upajak 15mg Tablet

Take Upajak exactly as prescribed by your doctor.

Because Upajak is an extended-release tablet:

• Take it orally once daily when prescribed.
• Swallow the tablet whole.
• Do not crush, split or chew the tablet unless your specific product information says otherwise.
• Try to take it at the same time each day.
• You may take upadacitinib with or without food unless your doctor gives different instructions.
• Do not take more than the prescribed amount.

If you miss a dose, follow the instructions provided by your healthcare professional or the product leaflet. Do not take extra tablets to compensate for a missed dose unless specifically instructed.

Upajak 15mg Tablet Side Effects

Like other prescription medicines, Upajak may cause side effects. Some people may experience:

• Upper respiratory tract infections
• Nausea
• Acne
• Headache
• Fever
• Cough
• Tiredness

The type and frequency of side effects can vary depending on the condition being treated and other medicines used with upadacitinib.

Serious Side Effects

Upadacitinib can increase the risk of serious infections and other potentially severe complications.

Contact a healthcare professional promptly if you develop:

• Persistent fever or chills
• Severe or worsening infection symptoms
• Shortness of breath or chest symptoms
• Unusual bruising or bleeding
• Severe abdominal pain
• Symptoms of an allergic reaction
• Sudden weakness, chest pain or other symptoms suggesting a cardiovascular problem

Official prescribing information also warns about serious infections, malignancies, major cardiovascular events, thrombosis, gastrointestinal perforation and laboratory abnormalities.

Upajak 15mg Precautions

Before starting Upajak, tell your doctor about your medical history and all medicines you use.

Particular care may be required if you:

• Have an active infection
• Have a history of tuberculosis or have been exposed to TB
• Have liver or kidney problems
• Have a history of blood clots
• Have cardiovascular risk factors
• Have certain cancers or a history of cancer
• Have gastrointestinal problems
• Are pregnant or planning pregnancy
• Are receiving vaccinations

Your doctor may recommend blood tests before and during treatment to monitor blood counts, liver enzymes and cholesterol levels.

Upadacitinib should generally not be used in people with active, serious infections. Live vaccines should also be avoided during treatment.

Upajak 15mg Tablet Drug Interactions

Upadacitinib can interact with medicines that affect the CYP3A4 enzyme.

Strong CYP3A4 inhibitors can increase upadacitinib exposure, while strong CYP3A4 inducers can reduce its exposure and potentially decrease its effectiveness. The Upajak prescribing information specifically advises against use with strong CYP3A4 inducers and recommends caution with strong CYP3A4 inhibitors during chronic treatment.

Tell your doctor about all prescription medicines, over-the-counter products and supplements you take before starting Upajak.

Do not start or stop another medicine without professional medical advice.

Upajak, Pregnancy and Breastfeeding

Upadacitinib may cause fetal harm based on animal studies. Women who can become pregnant should discuss pregnancy prevention and treatment options with their healthcare professional.

If you are pregnant, planning to become pregnant or breastfeeding, tell your doctor before using Upajak.

Your doctor can help determine whether continuing treatment is appropriate and whether another treatment option may be safer.

Upajak 15mg Storage

According to the manufacturer’s prescribing information, Upajak should be stored below 30°C in a cool, dry place.

Keep the medicine protected from light and away from children.

Always follow the storage instructions printed on the specific package you receive.

Upajak 15mg Manufacturer

Upajak 15mg Tablet is manufactured by Everest Pharmaceuticals Ltd., Bangladesh.

The manufacturer’s product information identifies Upajak as upadacitinib 15mg extended-release tablets and lists Everest Pharmaceuticals Ltd. as the manufacturer.

Manufacturer and packaging information can vary between markets, so check the product packaging before use.

Upajak 15mg Price in Pakistan

The Upajak 15mg Tablet price in Pakistan can vary depending on pack size, supplier, import status, availability and market conditions.

Since Upajak is a prescription medicine, the current price and availability should be confirmed before ordering.

Customers can check the latest product availability and pricing through Impo Medic.

Buy Upajak 15mg Tablet in Pakistan

If you are looking for Upajak 15mg in Pakistan, Impo Medic provides online product information and ordering support, subject to availability.

Before ordering, check the product name, strength, pack size and expiry information carefully. Upajak is a prescription medicine and should be used according to the instructions of a qualified healthcare professional.

Do not use Upajak simply because it has helped someone else with a similar condition. The appropriate treatment depends on your diagnosis, medical history and other medicines.

Why Choose Impo Medic?

• Easy access to medicine information
• Convenient online ordering
• Updated product availability
• Clear product and strength information
• Transparent pricing where available
• Support for imported medicines where applicable
• Responsible approach to prescription medicines

FAQs About Upajak 15mg Tablet (Upadacitinib)

What is Upajak 15mg used for?

Upajak 15mg contains upadacitinib and is used for certain inflammatory conditions, including rheumatoid arthritis and psoriatic arthritis, according to its product information.

What is the active ingredient in Upajak 15mg?

The active ingredient is upadacitinib. Each extended-release tablet contains 15mg of upadacitinib.

How often is Upajak 15mg taken?

For several approved inflammatory conditions, upadacitinib 15mg is taken once daily. The correct dose depends on the condition and the patient’s medical circumstances.

What are the common side effects of Upajak?

Possible side effects include upper respiratory tract infections, nausea, acne, headache, cough and fever. The risk and frequency can vary between patients.

Can Upajak cause serious infections?

Yes. Upadacitinib can increase the risk of serious infections. Patients should contact their healthcare professional if they develop symptoms of a serious infection.

Can Upajak be taken during pregnancy?

Upadacitinib may pose a risk to an unborn baby. If you are pregnant or planning pregnancy, discuss Upajak treatment with your doctor before taking it.

What is the price of Upajak 15mg in Pakistan?

The price can vary according to supplier, pack size and availability. Check Impo Medic for current pricing and availability.

Does Upajak require a prescription?

Yes. Upajak is a prescription medicine and should be used under the supervision of a qualified healthcare professional.

Legal & Medical Disclaimer

This article is for general educational purposes only and does not replace professional medical advice, diagnosis or treatment. Upajak 15mg can cause serious side effects and requires appropriate medical monitoring. Always use this medicine according to your doctor’s prescription and the official product information.