Description

Soranib Tablet 200mg (Sorafenib) – Uses, Dosage, Side Effects & Price in Pakistan

Soranib Tablet 200mg contains sorafenib, an oral targeted cancer medicine belonging to the kinase inhibitor class. Sorafenib is used to treat certain types of liver, kidney, and thyroid cancers. It works by blocking proteins involved in cancer-cell growth and the formation of new blood vessels that tumors need to grow.

Soranib 200mg is a prescription oncology medicine and should only be used under the supervision of a qualified oncologist.

What Is Soranib Tablet 200mg?

Soranib Tablet 200mg contains sorafenib 200mg as its active ingredient. Soranib is marketed by Cipla Ltd. and is available as an oral tablet. Product listings identify Soranib 200mg as a Cipla product containing sorafenib.

Sorafenib is a multikinase inhibitor that targets several signaling pathways involved in tumor growth and blood-vessel formation. This makes it a targeted therapy rather than traditional cytotoxic chemotherapy.

Soranib 200mg Uses

Sorafenib is approved for specific cancer conditions, including:

Liver Cancer

Soranib may be used for unresectable hepatocellular carcinoma (HCC), a type of liver cancer that cannot be removed through surgery.

Kidney Cancer

Sorafenib is also indicated for advanced renal cell carcinoma (RCC), a type of kidney cancer.

Thyroid Cancer

Soranib may be prescribed for locally recurrent or metastatic, progressive differentiated thyroid carcinoma (DTC) that is resistant to radioactive iodine treatment.

The appropriate treatment depends on the cancer type, stage, previous treatment, and overall condition of the patient.

How Does Sorafenib Work?

Sorafenib blocks several proteins called kinases that are involved in cancer-cell signaling. It also interferes with signaling pathways involved in angiogenesis, the process through which tumors develop new blood vessels.

By blocking these pathways, sorafenib can help slow cancer-cell growth and reduce the formation of new blood vessels that support tumor growth.

Soranib 200mg Dosage

The standard labeled dosage of sorafenib is 400mg twice daily, taken without food. Since each Soranib tablet contains 200mg of sorafenib, the standard regimen corresponds to two 200mg tablets per dose when prescribed by the treating physician.

However, the dose may be reduced or treatment temporarily interrupted if significant side effects occur.

Do not change the dose yourself. Your oncologist will determine the appropriate dose based on your cancer type, treatment response, laboratory results, and tolerance.

How to Take Soranib 200mg Tablet

• Take Soranib exactly as prescribed.
• Sorafenib should generally be taken without food.
• Take it at least 1 hour before or 2 hours after a meal.
• Swallow the tablets with water.
• Try to take the doses at approximately the same times each day.
• If you miss a dose, take the next dose at the normal scheduled time.
• Do not take an extra dose to compensate for a missed dose.

Treatment usually continues as long as the medicine is providing clinical benefit and side effects remain manageable.

Soranib 200mg Side Effects

Soranib can cause side effects, although they do not occur in every patient.

Common adverse reactions associated with sorafenib include:

• Diarrhea
• Fatigue
• Hand-foot skin reaction
• Rash
• Hair loss
• Loss of appetite
• Nausea
• Weight loss
• Abdominal or gastrointestinal discomfort
• High blood pressure
• Bleeding
• Infections

Tell your healthcare provider if side effects become persistent or difficult to manage.

Serious Side Effects and Warnings

High Blood Pressure

Sorafenib can cause or worsen hypertension. Blood pressure should be monitored regularly, particularly during the early stages of treatment.

Hand-Foot Skin Reaction

Pain, redness, swelling, tenderness, or peeling of the palms and soles may occur. Severe symptoms may require treatment interruption or dose adjustment.

Bleeding

Sorafenib may increase the risk of hemorrhage. Report unusual bleeding, blood in the urine, black stools, coughing up blood, or other concerning symptoms to your doctor promptly.

Heart Problems

Sorafenib has been associated with cardiovascular events, including cardiac ischemia and heart attack. Seek urgent medical attention for chest pain, severe breathing difficulty, or other symptoms of a cardiac emergency.

Severe Skin Reactions

Rare but serious dermatological reactions can occur. Severe blistering, peeling, or widespread skin reactions require immediate medical evaluation.

Soranib 200mg Precautions

Before starting Soranib, tell your doctor if you have:

• Heart disease or a history of heart problems
• High blood pressure
• A bleeding disorder
• Liver or kidney problems
• A planned surgical procedure
• A history of serious drug reactions
• Any other medical condition

Your oncologist may monitor blood pressure, blood tests, liver function, and other parameters throughout treatment.

Soranib 200mg Drug Interactions

Sorafenib can interact with other medicines. Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins, and herbal supplements you use.

Strong CYP3A4 inducers should generally be avoided because they may reduce sorafenib exposure. Other medicines may also affect bleeding, blood pressure, or cardiovascular risk during treatment.

Never start or stop another medicine without discussing it with your healthcare provider.

Pregnancy and Breastfeeding

Sorafenib may cause harm to an unborn baby. Women who can become pregnant should discuss appropriate contraception with their healthcare provider before and during treatment.

Breastfeeding is not recommended during treatment with sorafenib. The current prescribing information also recommends avoiding breastfeeding for 2 weeks after the last dose.

Soranib 200mg Storage

Store Soranib according to the instructions provided on the original packaging.

Sorafenib tablets are generally stored at controlled room temperature. The current U.S. prescribing information specifies 20°C to 25°C, with permitted excursions between 15°C and 30°C.

Keep the medicine away from excessive heat and moisture and out of the reach of children.

Soranib 200mg Manufacturer

Soranib 200mg is manufactured/marketed by Cipla Ltd., India. Current product listings identify Cipla as the manufacturer or marketer of Soranib 200mg, and Pakistani procurement documentation has also identified Soranib 200mg with Cipla Ltd.

Always check the original packaging for the manufacturer, batch number, expiry date, and country of origin.

Soranib 200mg Price in Pakistan

The price of Soranib 200mg in Pakistan can vary depending on pack size, importer, availability, and supplier.

For the latest Soranib 200mg price in Pakistan, customers should check the current product listing or contact the pharmacy for updated availability and pricing.

Buy Soranib 200mg Tablet in Pakistan

Soranib 200mg is a prescription cancer medicine and should be used only according to an oncologist’s treatment plan.

Before purchasing, check the product name, strength, packaging, batch number, expiry date, and manufacturer details. Do not change the prescribed dose based on the tablet strength or price.

Why Choose Impo Medic?

At Impo Medic, we aim to provide clear product information and access to imported medicines while maintaining a responsible approach to prescription oncology products.

• Clear and updated product information
• Imported medicine availability
• Transparent pricing where available
• Online ordering support
• Assistance with product availability
• Responsible guidance for prescription medicines

FAQs About Soranib Tablet 200mg (Sorafenib)

1. What is Soranib 200mg used for?

Soranib contains sorafenib and is used for certain liver, kidney, and differentiated thyroid cancers.

2. What is the active ingredient in Soranib 200mg?

The active ingredient is sorafenib 200mg.

3. What is the usual sorafenib dosage?

The standard labeled dose is 400mg twice daily without food, but your oncologist may adjust the dose depending on your condition and side effects.

4. Should Soranib be taken with food?

Sorafenib should generally be taken without food, at least 1 hour before or 2 hours after a meal.

5. What are common Soranib side effects?

Common side effects include diarrhea, fatigue, hand-foot skin reaction, rash, hair loss, decreased appetite, nausea, weight loss, hypertension, and bleeding.

6. Can Soranib cause high blood pressure?

Yes. Sorafenib can cause hypertension, so regular blood-pressure monitoring is recommended during treatment.

7. Is Soranib a chemotherapy medicine?

Soranib contains sorafenib, which is a targeted kinase inhibitor rather than traditional cytotoxic chemotherapy.

8. Can Soranib be used without a prescription?

No. Soranib is a prescription cancer medicine and should only be used under the supervision of a qualified healthcare professional.

Legal & Medical Disclaimer

This information is provided for educational purposes only and does not replace professional medical advice. Soranib Tablet 200mg (Sorafenib) should only be used under the supervision of a qualified healthcare professional. Do not start, stop, or change the dosage without consulting your doctor.