Description

LuciBru 140mg Tablet (Ibrutinib) Uses, Side Effects, Dosage & Price in Pakistan

LuciBru 140mg Tablet (Ibrutinib) is a prescription targeted cancer medicine used to treat certain blood cancers and immune-related conditions. It contains ibrutinib, a Bruton’s tyrosine kinase (BTK) inhibitor that blocks signals involved in the growth and survival of certain abnormal B cells.

Ibrutinib is used in adults with conditions such as chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), and Waldenström’s macroglobulinemia. It is also approved for adults and children aged 1 year and older with chronic graft-versus-host disease (cGVHD) after failure of one or more systemic treatments.

What is LuciBru 140mg Tablet?

LuciBru 140mg Tablet contains Ibrutinib 140mg. Ibrutinib belongs to a class of medicines called kinase inhibitors.

BTK is an important protein involved in B-cell receptor signaling. Some abnormal B cells depend on this signaling pathway for growth and survival. Ibrutinib binds to BTK and blocks its activity, which can interfere with the signals that help these abnormal cells multiply and survive.

LuciBru should be used under the supervision of a qualified doctor or oncologist.

LuciBru 140mg Tablet Uses

LuciBru 140mg may be prescribed for:

• Chronic lymphocytic leukemia (CLL)
• Small lymphocytic lymphoma (SLL)
• CLL/SLL with certain genetic features such as 17p deletion
• Waldenström’s macroglobulinemia (WM)
• Chronic graft-versus-host disease (cGVHD) after failure of one or more systemic therapies

The exact indication depends on the patient’s diagnosis, age, previous treatment, overall health, and treatment plan.

How Does LuciBru 140mg Work?

LuciBru contains ibrutinib, which is a BTK inhibitor.

BTK helps transmit signals that support the growth and survival of certain B cells. In some blood cancers, abnormal B cells rely heavily on these signals.

Ibrutinib forms a covalent bond with BTK and inhibits its enzymatic activity. By blocking this pathway, it can reduce signals that cancerous B cells need to survive and multiply.

LuciBru 140mg Tablet Dosage

The appropriate dose of ibrutinib depends on the condition being treated.

For many adult patients with CLL, SLL, or Waldenström’s macroglobulinemia, the recommended dose in current U.S. labeling is 420mg once daily. For adults and children aged 12 years and older with cGVHD, the recommended dose is also 420mg once daily. For children aged 1 to less than 12 years with cGVHD, dosing is based on body surface area.

Because LuciBru contains 140mg per tablet, a 420mg dose corresponds to three 140mg tablets when this dose is prescribed.

Your doctor may reduce, interrupt, or discontinue treatment depending on side effects, liver function, drug interactions, and other clinical factors.

Never change your dose without medical advice.

How to Take LuciBru 140mg

• Take LuciBru exactly as prescribed by your doctor.
• Take it at approximately the same time every day.
• Swallow the tablet whole with water.
• Do not crush, cut, break, or chew the tablet.
• Do not take more than the prescribed dose.
• If you miss a dose, follow your doctor’s or pharmacist’s instructions.
• Do not stop treatment without speaking with your healthcare provider.

Ibrutinib tablets and capsules should be swallowed whole.

LuciBru 140mg Tablet Side Effects

Like other cancer medicines, LuciBru may cause side effects. Possible side effects of ibrutinib include:

• Diarrhea
• Tiredness
• Nausea
• Muscle or joint pain
• Rash
• Bruising
• Headache
• Fever
• Upper respiratory infections
• High blood pressure
• Decreased blood cell counts

The severity of side effects can vary from person to person.

Serious Side Effects

Ibrutinib can cause serious adverse effects, including:

• Serious bleeding or hemorrhage
• Infections
• Abnormal heart rhythms
• Heart failure
• High blood pressure
• Low blood cell counts
• Tumor lysis syndrome
• Development of second primary cancers
• Serious fetal harm during pregnancy

Contact your doctor immediately if you experience significant bleeding, severe infection symptoms, chest pain, fainting, unusual heartbeat, severe shortness of breath, or other serious symptoms.

Important Precautions

Before taking LuciBru 140mg, tell your doctor if you have:

• Heart disease
• Abnormal heart rhythm
• High blood pressure
• Liver problems
• A history of bleeding
• Recurrent infections
• Any other serious medical condition

Tell your doctor about every medicine, vitamin, supplement, and herbal product you take.

Ibrutinib interacts with medicines that affect CYP3A. Strong CYP3A inhibitors may require dose modification, while strong CYP3A inducers should generally be avoided.

Your doctor may monitor your blood counts, blood pressure, heart health, liver function, and signs of infection or bleeding during treatment.

LuciBru 140mg and Pregnancy

Ibrutinib may cause harm to an unborn baby. Women who can become pregnant should discuss effective contraception with their healthcare provider before and during treatment.

Tell your doctor immediately if pregnancy occurs while taking LuciBru.

Breastfeeding is not recommended during treatment with ibrutinib according to current prescribing information.

LuciBru 140mg Tablet Price in Pakistan

The LuciBru 140mg Tablet price in Pakistan may vary depending on the manufacturer, pack size, imported stock, supplier, and current market availability.

Because LuciBru is a specialized prescription medicine, its price and availability can change. Patients should confirm the latest LuciBru 140mg Tablet price in Pakistan with a reliable medicine supplier before ordering.

Buy LuciBru 140mg Tablet in Pakistan

Looking to buy LuciBru 140mg Tablet (Ibrutinib) in Pakistan? Impo Medic provides information and availability support for specialized and imported medicines.

You can contact Impo Medic to check the current availability, price, and ordering information for LuciBru 140mg Tablet.

Ibrutinib is a prescription medicine and should only be used according to the treatment plan provided by your doctor or oncologist.

Why Choose Impo Medic?

Impo Medic provides easy-to-understand information about specialized and imported medicines for patients in Pakistan. Our medicine pages explain important details such as uses, dosage, side effects, precautions, and general availability in simple language.

If you are searching for LuciBru 140mg Tablet (Ibrutinib), Impo Medic can help you understand the medicine and check its availability. For blood-cancer treatment, always follow your doctor’s prescription and recommended monitoring schedule.

FAQs About LuciBru 140mg Tablet (Ibrutinib)

What is LuciBru 140mg Tablet used for?

LuciBru contains ibrutinib and may be used for CLL, SLL, Waldenström’s macroglobulinemia, and certain cases of chronic graft-versus-host disease.

How does LuciBru 140mg work?

Ibrutinib blocks Bruton’s tyrosine kinase (BTK), a protein involved in signaling that helps certain abnormal B cells grow and survive.

What is the usual adult dose of ibrutinib?

For many adult patients with CLL/SLL or Waldenström’s macroglobulinemia, the labeled dose is 420mg once daily. Your doctor may prescribe a different dose depending on your condition and other factors.

How many LuciBru 140mg tablets make 420mg?

Three 140mg tablets equal 420mg. However, only take the number of tablets specifically prescribed by your doctor.

Can LuciBru 140mg be crushed?

No. Ibrutinib tablets should be swallowed whole and should not be cut, crushed, broken, or chewed.

What are the common side effects of LuciBru?

Possible side effects include diarrhea, tiredness, nausea, muscle or joint pain, rash, bruising, infections, and changes in blood counts.

Can LuciBru cause bleeding?

Yes. Ibrutinib can increase the risk of bleeding, including serious hemorrhage. Tell your doctor about any unusual bruising or bleeding.

Is LuciBru 140mg available in Pakistan?

Availability can vary according to imported stock and supplier availability. You can contact Impo Medic to check the current availability and ordering information.