Description

LuciAle 150mg Capsule (Alectinib) Uses, Side Effects, Dosage & Price in Pakistan

LuciAle 150mg Capsule (Alectinib) is a targeted cancer medicine used for certain patients with ALK-positive non-small cell lung cancer (NSCLC). It contains alectinib, an ALK tyrosine kinase inhibitor that blocks abnormal ALK signaling involved in the growth and survival of cancer cells.

Alectinib may be used for adults with ALK-positive metastatic NSCLC and, in selected patients after surgical removal of the tumor, as adjuvant treatment to reduce the risk of the cancer returning. ALK status should be confirmed with an appropriate approved test before treatment.

What is LuciAle 150mg Capsule?

LuciAle 150mg Capsule contains Alectinib 150mg, a targeted therapy belonging to the tyrosine kinase inhibitor class.

Alectinib specifically targets the anaplastic lymphoma kinase (ALK) protein. Certain lung cancers contain ALK rearrangements that can cause abnormal signals promoting cancer-cell growth.

By blocking ALK activity, alectinib interferes with these signals and may help slow or stop the growth of ALK-positive cancer cells.

LuciAle 150mg Capsule Uses

LuciAle 150mg may be prescribed for adults with ALK-positive non-small cell lung cancer.

Its approved uses include:

• Treatment of ALK-positive metastatic NSCLC
• Adjuvant treatment after surgical removal of certain ALK-positive NSCLC tumors
• Helping reduce the risk of cancer recurrence after surgery in eligible patients

For adjuvant treatment, current U.S. labeling includes adults whose resected tumors are at least 4 cm or are node-positive. For metastatic disease, treatment is selected based on confirmed ALK positivity.

How Does LuciAle 150mg Work?

LuciAle contains alectinib, which blocks the activity of abnormal ALK proteins.

Some NSCLC tumors contain ALK gene rearrangements that continuously activate signals telling cancer cells to grow and survive. Alectinib binds to and inhibits ALK, disrupting these cancer-promoting signals.

This targeted action can help reduce cancer-cell growth and may slow the progression of ALK-positive NSCLC.

LuciAle 150mg Capsule Dosage

The commonly recommended adult dose of alectinib is 600mg twice daily with food. Since each LuciAle capsule contains 150mg, this standard dose corresponds to four 150mg capsules per dose, taken twice daily.

However, your oncologist may reduce the dose if you experience certain side effects or have specific medical conditions.

For patients with severe hepatic impairment, the recommended dose in current U.S. labeling is 450mg twice daily.

Do not change your dose without your doctor’s instructions.

How to Take LuciAle 150mg

• Take LuciAle exactly as prescribed by your oncologist.
• Take it twice daily with food.
• Try to take the doses at approximately the same times every day.
• Swallow the capsules whole.
• Do not open, crush, or dissolve the capsule contents.
• If you miss a dose, skip it and take the next dose at the normal scheduled time.
• If you vomit after taking a dose, do not take an extra dose.
• Continue treatment as directed by your oncologist.

LuciAle 150mg Capsule Side Effects

Like other cancer medicines, LuciAle may cause side effects. Common side effects associated with alectinib include:

• Constipation
• Fatigue
• Muscle pain
• Swelling or edema
• Rash
• Cough
• Headache
• Diarrhea
• Weight gain

The current prescribing information lists hepatotoxicity, constipation, fatigue, myalgia, edema, rash, and cough among the most common adverse reactions.

Serious Side Effects

Alectinib can also cause serious side effects, including:

• Liver problems
• Interstitial lung disease or pneumonitis
• Slow heart rate (bradycardia)
• Severe muscle pain or muscle injury
• Increased creatine phosphokinase (CPK)
• Hemolytic anemia
• Kidney problems
• Serious fetal harm during pregnancy

Contact your doctor promptly if you develop difficulty breathing, new or worsening cough, yellowing of the skin or eyes, severe muscle pain or weakness, fainting, unusual tiredness, or other concerning symptoms.

Important Precautions

Before taking LuciAle 150mg, tell your doctor if you have:

• Liver disease
• Lung or breathing problems
• Slow or irregular heartbeat
• Kidney problems
• Previous muscle problems

Your doctor may regularly monitor liver function, heart rate, blood pressure, kidney function, and CPK levels during treatment.

Current prescribing information recommends liver tests every two weeks during the first three months and then monthly or as clinically indicated. CPK monitoring is also recommended during the early treatment period and when unexplained muscle symptoms occur.

Alectinib can also make the skin more sensitive to sunlight. Patients should take sun-protection measures during treatment and for at least 7 days after the final dose.

LuciAle 150mg and Pregnancy

Alectinib may cause harm to an unborn baby. Women who can become pregnant should use effective contraception during treatment and for at least 1 week after the final dose.

Male patients with female partners who can become pregnant should use effective contraception during treatment and for 3 months after the final dose.

Breastfeeding is not recommended during treatment with alectinib and for 1 week after the last dose.

LuciAle 150mg Capsule Price in Pakistan

The LuciAle 150mg Capsule price in Pakistan can vary depending on the manufacturer, pack size, imported stock, supplier, and availability.

Because alectinib is a specialized prescription cancer medicine, its price may change over time. Patients should confirm the latest LuciAle 150mg Capsule price in Pakistan with a reliable specialized medicine supplier before ordering.

Buy LuciAle 150mg Capsule in Pakistan

Looking to buy LuciAle 150mg Capsule (Alectinib) in Pakistan? Impo Medic provides information and availability support for specialized and imported medicines.

You can contact Impo Medic to check the latest availability, price, and ordering information for LuciAle 150mg Capsule. Alectinib is a prescription cancer medicine and should only be used under the supervision of a qualified oncologist.

Do not start, stop, or change your LuciAle dosage without medical advice.

Why Choose Impo Medic?

Impo Medic provides easy-to-understand information about specialized and imported medicines for patients in Pakistan. Our medicine pages explain important details such as uses, dosage, side effects, precautions, and general availability in simple language.

If you are searching for LuciAle 150mg Capsule (Alectinib), Impo Medic can help you understand the medicine and check its availability. For cancer treatment, always follow the treatment plan and monitoring schedule recommended by your oncologist.

Frequently Asked Questions (FAQs)

What is LuciAle 150mg Capsule used for?

LuciAle 150mg contains alectinib and is used for selected adults with ALK-positive non-small cell lung cancer, including certain metastatic cases and eligible patients after surgery.

How does LuciAle 150mg work?

Alectinib blocks abnormal ALK signaling that can help cancer cells grow and survive. Blocking this pathway may slow the growth of ALK-positive cancer cells.

What is the usual dose of LuciAle?

The usual adult dose of alectinib is 600mg twice daily with food. Since each capsule contains 150mg, the standard dose equals four 150mg capsules twice daily. Your doctor may prescribe a lower dose if necessary.

Can LuciAle 150mg be taken without food?

Alectinib should be taken with food. Taking it as directed helps ensure proper administration of the medicine.

What are the common side effects of LuciAle?

Common side effects include constipation, fatigue, muscle pain, swelling, rash, cough, headache, diarrhea, and weight gain.

What should I do if I miss a LuciAle dose?

Skip the missed dose and take the next dose at the regular scheduled time. Do not take an extra dose to make up for the missed one.

Can LuciAle be used for all lung cancer patients?

No. Alectinib is specifically used for ALK-positive NSCLC. Appropriate testing is needed to confirm ALK positivity before treatment.

Is LuciAle 150mg available in Pakistan?

Availability may vary depending on imported stock and supplier availability. You can contact a reliable specialized medicine supplier such as Impo Medic to check current availability.