Description

Lorbrexen 100mg Tablet (Lorlatinib) – Uses, Side Effects, Dosage & Price in Pakistan

Lorbrexen 100mg Tablet (Lorlatinib) is a prescription targeted cancer medicine used to treat adults with ALK-positive metastatic non-small cell lung cancer (NSCLC). It contains lorlatinib, a kinase inhibitor that works by blocking abnormal signals responsible for the growth and spread of certain cancer cells.

Lorbrexen 100mg Tablet should only be used under the supervision of a qualified oncologist. The doctor may adjust the dose depending on the patient’s medical condition, kidney or liver function, other medicines, and treatment response.

What is Lorbrexen 100mg Tablet?

Lorbrexen 100mg Tablet contains Lorlatinib 100mg, a targeted kinase inhibitor. It is designed for certain patients whose non-small cell lung cancer has an abnormal ALK (anaplastic lymphoma kinase) gene.

Lorlatinib blocks signals from abnormal ALK proteins that can help cancer cells grow and spread. Because it is a targeted treatment, it is generally prescribed when the cancer has been confirmed to be ALK-positive through appropriate testing.

Lorbrexen 100mg Tablet Uses

Lorbrexen 100mg Tablet is used for adults with ALK-positive metastatic non-small cell lung cancer (NSCLC).

It may be prescribed when the cancer has spread to other parts of the body. Your oncologist will determine whether lorlatinib is appropriate based on molecular testing, cancer stage, previous treatment, and your overall health.

Main use of Lorbrexen 100mg

• ALK-positive metastatic non-small cell lung cancer
• Targeted treatment of cancers driven by abnormal ALK signaling
• Treatment when prescribed by an oncologist based on appropriate cancer testing

How Does Lorbrexen 100mg Work?

Lorlatinib is a kinase inhibitor that blocks abnormal ALK-related signaling inside cancer cells.

ALK signaling can promote the multiplication and survival of cancer cells. By inhibiting this abnormal signaling, lorlatinib can help slow the growth and spread of ALK-positive lung cancer.

Lorlatinib is also designed to reach the central nervous system, which is important because ALK-positive lung cancer can spread to the brain.

Lorbrexen 100mg Tablet Dosage

The recommended dose of lorlatinib for adults with ALK-positive metastatic NSCLC is 100mg once daily, taken orally. Patients with severe liver or kidney impairment may require a lower dose according to their doctor’s assessment.

Do not change the dose or stop Lorbrexen without speaking with your oncologist.

How to Take Lorbrexen 100mg Tablet

• Take Lorbrexen exactly as prescribed.
• Take it once daily at approximately the same time each day.
• It can be taken with or without food.
• Swallow the tablet whole with water.
• Do not crush, chew, or split the tablet.
• If you vomit after taking a dose, do not take another dose.
• If you miss a dose, take it when you remember unless it is within 4 hours of the next scheduled dose. Do not take two doses together.

Lorbrexen 100mg Tablet Side Effects

Like other targeted cancer medicines, Lorbrexen 100mg Tablet can cause side effects. Common side effects of lorlatinib may include:

• Weight gain
• Swelling of the arms, legs, hands, or feet
• Tiredness
• Nausea
• Diarrhea
• Constipation
• Muscle, joint, or bone pain
• Peripheral neuropathy
• Changes in cholesterol and triglyceride levels
• Mood or cognitive changes

Some side effects can be serious. Lorlatinib may cause central nervous system effects, high cholesterol or triglycerides, heart rhythm problems, high blood pressure, high blood sugar, and lung inflammation.

Seek medical attention promptly if you experience severe breathing problems, seizures, significant confusion, hallucinations, serious mood changes, chest pain, fainting, or other unusual symptoms.

Important Precautions

Before taking Lorbrexen 100mg Tablet, tell your doctor about all medicines, vitamins, supplements, and herbal products you use.

Your doctor may monitor:

• Blood pressure
• Cholesterol and triglyceride levels
• Blood glucose
• Heart rhythm
• Liver and kidney function
• Neurological or mental changes
• Lung-related symptoms

Lorlatinib has important drug interactions. Strong CYP3A inducers are contraindicated because of the risk of serious liver toxicity. Always provide your doctor with a complete list of your medicines before starting treatment.

Lorbrexen 100mg and Pregnancy

Lorlatinib can cause harm to an unborn baby. Women who can become pregnant should discuss effective non-hormonal contraception with their healthcare provider during treatment and for the recommended period after treatment.

Lorlatinib may also reduce the effectiveness of hormonal contraceptives. Breastfeeding is not recommended during treatment and for the specified period after the final dose.

Lorbrexen 100mg Tablet Price in Pakistan

The Lorbrexen 100mg Tablet price in Pakistan may vary depending on availability, supplier, pack size, and import status.

Because lorlatinib is a specialized prescription cancer medicine, its availability and price may change. Patients should confirm the current Lorbrexen 100mg Tablet price in Pakistan with a reliable medicine supplier or pharmacy.

Buy Lorbrexen 100mg Tablet in Pakistan

Looking to buy Lorbrexen 100mg Tablet (Lorlatinib) in Pakistan? Impo Medic provides information and availability support for specialized and imported medicines. You can contact Impo Medic to check the current availability, price, and ordering details for Lorbrexen 100mg Tablet.

Lorbrexen is a prescription cancer medicine and should only be purchased and used according to the advice of a qualified oncologist. Do not start or change treatment without professional medical guidance.

Why Choose Impo Medic?

Impo Medic provides useful information about specialized and imported medicines for patients in Pakistan. Our medicine pages explain important details such as uses, dosage, precautions, side effects, and general availability in simple language.

If you are searching for Lorbrexen 100mg Tablet (Lorlatinib), Impo Medic can help you understand the medicine and check its availability. For cancer treatment, always follow the treatment plan prescribed by your oncologist.

Frequently Asked Questions (FAQs)

What is Lorbrexen 100mg Tablet used for?

Lorbrexen 100mg Tablet contains lorlatinib and is used to treat adults with ALK-positive metastatic non-small cell lung cancer.

How does Lorbrexen 100mg work?

Lorlatinib blocks abnormal ALK-related kinase signaling that can help cancer cells grow and spread.

What is the usual dose of Lorbrexen?

The recommended dose for adults with ALK-positive metastatic NSCLC is 100mg once daily. The doctor may prescribe a lower dose in certain patients with severe kidney or liver impairment.

Can Lorbrexen 100mg be taken with food?

Yes. Lorlatinib can be taken with or without food.

What are the common side effects of Lorbrexen?

Common side effects may include weight gain, swelling, tiredness, nausea, diarrhea, constipation, muscle or joint pain, neuropathy, and changes in blood lipid levels.

Can Lorbrexen cause mood or memory changes?

Yes. Lorlatinib can cause central nervous system effects, including cognitive, mood, speech, sleep, and mental-status changes. Inform your doctor immediately if you notice significant changes.

What should I do if I miss a dose?

Take the missed dose when remembered unless it is within 4 hours of the next scheduled dose. Do not take two doses together.

Is Lorbrexen 100mg available in Pakistan?

Availability can vary because lorlatinib is a specialized cancer medicine. Patients can contact a reliable oncology medicine supplier or Impo Medic to check current availability.