Description

Fruquin 5mg Capsule (Fruquintinib) – Uses, Side Effects, Dosage & Price in Pakistan

Fruquin 5mg Capsule (Fruquintinib) is a prescription targeted cancer medicine used to treat certain adults with metastatic colorectal cancer (mCRC). It contains fruquintinib, a kinase inhibitor that works by blocking signals involved in the growth of blood vessels that supply cancer cells.

Fruquintinib is generally used in patients whose metastatic colorectal cancer has already been treated with certain chemotherapy and targeted medicines. It should only be used under the supervision of a qualified oncologist.

What is Fruquin 5mg Capsule?

Fruquin 5mg Capsule contains Fruquintinib 5mg, an oral kinase inhibitor. It is a targeted cancer medicine used for selected adults with metastatic colorectal cancer.

Fruquintinib works mainly by blocking vascular endothelial growth factor receptors (VEGFRs), which are involved in the formation of new blood vessels. Cancer cells need blood vessels to receive oxygen and nutrients, so blocking these signals can help slow tumor growth and progression.

The medicine is available as 1mg and 5mg capsules in the U.S. labeling, with the 5mg strength used as the recommended starting dose for approved treatment.

Fruquin 5mg Capsule Uses

Fruquin 5mg Capsule is used to treat metastatic colorectal cancer in adults who have previously received certain anticancer treatments.

The FDA-approved indication includes patients who have previously been treated with:

• Fluoropyrimidine-based chemotherapy
• Oxaliplatin-based chemotherapy
• Irinotecan-based chemotherapy
• An anti-VEGF therapy
• An anti-EGFR therapy when the cancer is RAS wild-type and such treatment is medically appropriate

Your oncologist will determine whether fruquintinib is appropriate based on your cancer type, previous treatment, overall health, and response to earlier medicines.

How Does Fruquin 5mg Work?

Fruquintinib is a VEGFR kinase inhibitor. It blocks signaling through vascular endothelial growth factor receptors that help tumors develop new blood vessels.

By reducing these signals, fruquintinib can help limit the blood supply that supports cancer growth. This may slow the progression of metastatic colorectal cancer.

Fruquin 5mg Capsule Dosage

The recommended dose of fruquintinib is 5mg once daily for the first 21 days of each 28-day treatment cycle, followed by a 7-day break. Treatment may continue until the cancer progresses or side effects become unacceptable.

The dose may be reduced by the doctor if significant side effects occur. The labeled dose-reduction levels are 4mg once daily and then 3mg once daily.

How to Take Fruquin 5mg Capsule

• Take Fruquin exactly as prescribed by your oncologist.
• Take it once daily at approximately the same time.
• It can be taken with or without food.
• Swallow the capsule whole.
• Do not crush, chew, or open the capsule.
• Follow the 21-days-on and 7-days-off treatment schedule prescribed by your doctor.
• If vomiting occurs after taking the medicine, do not take an extra dose.
• If you miss a dose and less than 12 hours have passed, follow the prescribing instructions; never take two doses on the same day.

Fruquin 5mg Capsule Side Effects

Like other targeted cancer medicines, Fruquin 5mg Capsule can cause side effects. Common side effects of fruquintinib may include:

• High blood pressure
• Hand-foot syndrome
• Protein in the urine
• Abdominal pain
• Diarrhea
• Tiredness or weakness
• Voice changes
• Decreased appetite
• Nausea

The FDA has also highlighted risks including bleeding, infections, impaired wound healing, and liver problems.

Contact your healthcare provider promptly if you experience severe bleeding, significant abdominal pain, severe diarrhea, chest pain, breathing difficulty, severe swelling, or other unusual symptoms.

Important Precautions

Before taking Fruquin 5mg Capsule, tell your doctor about your complete medical history and all medicines you currently use.

Special care may be needed if you have:

• High blood pressure
• Bleeding problems
• Liver problems
• Kidney problems
• An active infection
• A recent or planned surgery

Blood pressure should be controlled before starting treatment and monitored during therapy. Your doctor may also monitor liver function and other laboratory tests during treatment.

Fruquintinib can affect wound healing. According to the prescribing information, patients should generally stop treatment at least 2 weeks before planned surgery, with the timing of restarting treatment decided by the healthcare provider.

Fruquin 5mg and Pregnancy

Fruquintinib may cause harm to an unborn baby. Women who can become pregnant should discuss effective contraception with their healthcare provider during treatment and for the recommended period after treatment.

Patients should tell their doctor if they are pregnant, planning pregnancy, or breastfeeding before starting Fruquin.

Fruquin 5mg Capsule Price in Pakistan

The Fruquin 5mg Capsule price in Pakistan may vary depending on the supplier, pack size, availability, and import status.

Because fruquintinib is a specialized cancer medicine, its availability and price can change. Contact a reliable pharmacy or specialized medicine supplier for the latest Fruquin 5mg Capsule price in Pakistan.

Buy Fruquin 5mg Capsule in Pakistan

Looking to buy Fruquin 5mg Capsule (Fruquintinib) in Pakistan? Impo Medic provides information and availability support for specialized and imported medicines. You can contact Impo Medic to check the current availability, price, and ordering details for Fruquin 5mg Capsule.

As Fruquin contains a prescription cancer medicine, it should only be purchased and used according to the advice of a qualified oncologist. Do not start, stop, or change the dose without medical guidance.

Why Choose Impo Medic?

Impo Medic provides useful information about specialized and imported medicines for patients in Pakistan. Our medicine pages explain important details such as uses, dosage, precautions, side effects, and general availability in simple language.

If you are searching for Fruquin 5mg Capsule (Fruquintinib), Impo Medic can help you understand the medicine and check its availability. Always follow your oncologist’s treatment plan when using cancer medicines.

Frequently Asked Questions (FAQs)

What is Fruquin 5mg Capsule used for?

Fruquin 5mg Capsule contains fruquintinib and is used for certain adults with metastatic colorectal cancer who have previously received specified chemotherapy and targeted treatments.

How does Fruquin 5mg work?

Fruquintinib blocks VEGFR-related signaling that helps tumors form new blood vessels. This can help slow the growth and spread of cancer cells.

How often should Fruquin 5mg be taken?

The recommended dose is 5mg once daily for 21 days of a 28-day cycle, followed by 7 days without treatment. Your oncologist may adjust the dose depending on your response and side effects.

Can Fruquin 5mg be taken with food?

Yes. Fruquintinib can be taken with or without food.

What are the common side effects of Fruquin?

Common side effects include high blood pressure, hand-foot syndrome, proteinuria, diarrhea, abdominal pain, voice changes, and weakness or fatigue.

What should I do if I miss a dose?

Follow your prescribing instructions. If less than 12 hours have passed since the missed dose, the dose may still be taken; if more time has passed, the next scheduled dose should generally be taken. Do not take two doses on the same day.

Is Fruquin 5mg available in Pakistan?

Availability can vary because fruquintinib is a specialized cancer medicine. Contact a reliable oncology medicine supplier or Impo Medic to check current availability and pricing.

Can I stop Fruquin 5mg when I feel better?

No. Do not stop Fruquin without speaking with your oncologist. Your doctor will decide how long treatment should continue based on your condition, response, and side effects.