Description

Abyrone 250mg Tablet (Abiraterone Acetate) Uses, Dosage, Side Effects & Price in Pakistan

Abyrone 250mg Tablet contains abiraterone acetate, a prescription anti-androgen medicine used in the treatment of certain forms of advanced prostate cancer. Abiraterone works by reducing the production of androgens, including testosterone, which can support the growth of prostate cancer cells. It is generally used together with prednisone or prednisolone and, where indicated, androgen-deprivation therapy (ADT).

Abyrone 250mg Tablet (Abirateron Acetate) is manufactured by Tongmeng (Lao) Pharmaceutical & Food Co., Ltd. and is available as a 250mg tablet. The manufacturer’s product information identifies Abyrone as abiraterone 250mg, while current product listings show a 120-tablet presentation.

What Is Abyrone 250mg Tablet?

Abyrone 250mg is an oral hormonal cancer medicine containing abiraterone acetate 250mg. Abiraterone acetate is a prodrug that is converted in the body to abiraterone, which inhibits the CYP17 enzyme involved in androgen production. By lowering androgen production, the medicine can help slow the growth and progression of certain prostate cancers.

Product details:

• Brand: Abyrone
• Strength: 250mg
• Active ingredient: Abiraterone acetate
• Dosage form: Tablet
• Route: Oral
• Manufacturer: Tongmeng (Lao) Pharmaceutical & Food Co., Ltd.
• Pack size: 120 tablets
• Medicine class: Anti-androgen / hormonal cancer therapy
• Prescription status: Prescription medicine

Abyrone 250mg Uses

Abyrone 250mg Tablet (Abirateron Acetate) is used for certain types of advanced or metastatic prostate cancer. Depending on the patient’s disease stage and previous treatment, abiraterone may be used for metastatic hormone-sensitive prostate cancer or metastatic castration-resistant prostate cancer.

1. Metastatic Hormone-Sensitive Prostate Cancer

Abiraterone can be used in adult men with newly diagnosed high-risk metastatic hormone-sensitive prostate cancer in combination with androgen-deprivation therapy and a corticosteroid such as prednisone or prednisolone.

2. Metastatic Castration-Resistant Prostate Cancer

Abyrone may also be prescribed for metastatic castration-resistant prostate cancer (mCRPC), including patients whose disease has progressed despite androgen-deprivation therapy. Specific treatment selection depends on previous therapies and the patient’s clinical condition.

3. Hormonal Control of Prostate Cancer

Unlike traditional chemotherapy, abiraterone works by interfering with androgen production. Since prostate cancer can be stimulated by male hormones, reducing androgen availability may help slow cancer progression.

How Does Abiraterone Acetate Work?

Abyrone contains abiraterone acetate, which is converted to active abiraterone inside the body.

Abiraterone blocks CYP17 (17α-hydroxylase/C17,20-lyase), an enzyme involved in androgen biosynthesis. This reduces androgen production in the testes, adrenal glands and prostate tumor tissue. Lower androgen levels can reduce hormonal stimulation of prostate cancer cells.

Because abiraterone can also reduce cortisol production and increase mineralocorticoid activity, treatment is normally combined with a corticosteroid such as prednisone or prednisolone to help manage these hormonal effects.

Abyrone 250mg Tablet Dosage

The usual total daily dose of abiraterone acetate for approved indications is 1,000mg once daily. With 250mg tablets, this corresponds to four tablets per day. However, the exact treatment regimen must be prescribed by the patient’s oncologist.

Abyrone should be taken:

• Once daily as prescribed
• On an empty stomach
• At least 2 hours after food
• With no food for at least 1 hour after taking the tablets
• With the prescribed prednisone or prednisolone regimen

Taking abiraterone with food can substantially increase its exposure and may increase the risk of adverse reactions.

Do not change the dose or stop prednisone/prednisolone without medical advice.

How to Take Abyrone 250mg

Swallow the tablets whole with water. Do not crush, chew, or break them unless specifically instructed by a healthcare professional.

Abyrone should be taken at approximately the same time each day. If a dose is missed, follow the instructions provided by the treating doctor or product information rather than taking an extra dose without medical advice.

Abiraterone treatment is generally continued as long as the patient is benefiting from therapy and side effects remain manageable, according to the oncologist’s treatment plan.

Abyrone 250mg Tablet Side Effects

Like other cancer medicines, Abyrone can cause side effects. Some are related to reduced cortisol production and increased mineralocorticoid activity.

Commonly reported effects can include:

• High blood pressure
• Low potassium levels
• Fluid retention or swelling
• Fatigue
• Joint pain
• Nausea
• Diarrhea
• Vomiting
• Headache
• Hot flushes
• Increased liver enzymes

Abiraterone may also cause more serious problems, including hepatotoxicity, severe hypertension, hypokalemia, fluid retention and cardiac-related complications. Regular monitoring can help detect problems early.

Contact the treating doctor promptly if there is severe swelling, difficulty breathing, persistent weakness, yellowing of the skin or eyes, dark urine, significant abdominal discomfort, or other concerning symptoms.

Important Precautions

Before starting Abyrone 250mg, tell your doctor if you have:

• Liver disease
• Heart disease or heart failure
• High blood pressure
• Low potassium levels
• A history of fluid retention
• Any previous reaction to abiraterone
• Other prescription or non-prescription medicines

Liver function should be monitored during treatment because abiraterone can cause liver toxicity. Blood pressure, potassium levels and signs of fluid retention may also require regular monitoring.

Women who are pregnant or may become pregnant should not handle abiraterone tablets without appropriate protection because the medicine may pose a risk to a developing fetus. Abiraterone is intended for use in male patients under appropriate medical supervision.

Abyrone 250mg Tablet Drug Interactions

Abiraterone may interact with other medicines, so provide your doctor with a complete list of all medicines and supplements you use.

Particular attention may be required with medicines that can affect:

• Liver enzymes responsible for drug metabolism
• Heart rhythm
• Potassium levels
• Blood pressure
• Liver function

Do not start or stop another medicine during Abyrone treatment without consulting your doctor or pharmacist.

Abyrone 250mg and Prednisone

Abyrone is generally prescribed together with prednisone or prednisolone because abiraterone inhibits CYP17 and can cause hormonal changes, including increased mineralocorticoid activity. Corticosteroid therapy helps reduce these effects.

Patients should take the corticosteroid exactly as prescribed. Suddenly stopping a corticosteroid without medical advice may cause complications.

Abyrone 250mg Tablet Storage

Store Abyrone according to the storage instructions provided on the original packaging.

Keep the tablets:

• In their original packaging
• Away from excessive heat and moisture
• Out of reach of children
• Protected from unsuitable storage conditions

Do not use tablets if the packaging is damaged or if the medicine has passed its expiry date.

For the exact storage temperature of your specific pack, follow the manufacturer’s packaging or ask a pharmacist.

Abyrone 250mg Price in Pakistan

The price of Abyrone 250mg Tablet in Pakistan can vary depending on availability, importer, supplier, and market conditions.

At the time of checking, Medicine Waly Dost listed Abirateron Acetate Abyrone Tablet 250mg at Rs. 39,000, although medicine prices and stock can change.

For the latest Abyrone 250mg price in Pakistan, confirm the current price and availability before placing an order.

Buy Abyrone 250mg in Pakistan

Abyrone 250mg is a prescription oncology medicine and should be used only according to the treatment plan provided by an oncologist.

When purchasing an imported cancer medicine, check:

• Brand and active ingredient
• Strength of the tablets
• Batch number
• Expiry date
• Original packaging
• Storage conditions
• Supplier reliability

Patients should not purchase or use abiraterone without appropriate medical supervision.

Why Choose Impo Medic?

Impo Medic focuses on helping customers access imported and specialty medicines in Pakistan.

When ordering Abyrone 250mg, customers can look for:

• Genuine imported medicines
• Clear product and strength information
• Secure packaging
• Nationwide delivery options
• Customer support for product availability
• Prescription-based medicine guidance

For oncology medicines, authenticity, correct strength, and appropriate handling are especially important.

FAQs About Abyrone 250mg Tablet (Abirateron Acetate)

What is Abyrone 250mg Tablet used for?

Abyrone 250mg contains abiraterone acetate and is used with appropriate accompanying therapy for certain forms of advanced or metastatic prostate cancer.

What is the active ingredient in Abyrone 250mg?

The active ingredient is abiraterone acetate 250mg. The manufacturer identifies Abyrone as an abiraterone 250mg product.

How many Abyrone 250mg tablets are usually taken daily?

The commonly recommended total abiraterone dose is 1,000mg once daily, which equals four 250mg tablets. The patient’s oncologist should confirm the appropriate regimen.

Should Abyrone 250mg be taken with food?

No. Abiraterone should be taken on an empty stomach because food can substantially increase its exposure. The standard instructions are at least 2 hours after food and at least 1 hour before eating again.

Is Abyrone 250mg chemotherapy?

Abyrone is not conventional cytotoxic chemotherapy. It is a hormonal/androgen biosynthesis inhibitor that works by reducing androgen production, which can help slow prostate cancer growth.

Does Abyrone 250mg need to be taken with prednisone?

Abiraterone is generally prescribed with prednisone or prednisolone according to the specific prostate cancer indication and treatment plan. Do not change or stop the corticosteroid without medical advice.

What are the main side effects of Abyrone?

Important potential side effects include high blood pressure, low potassium, fluid retention, fatigue and liver problems. Regular monitoring is important during treatment.

Where can I check the latest Abyrone 250mg price in Pakistan?

The price can change according to stock and supplier. Check the current product listing or contact the pharmacy before ordering to confirm the latest price and availability.

Medical Disclaimer

This article is intended for educational and informational purposes only. Abyrone 250mg is a prescription cancer medicine and should be used under the supervision of a qualified oncologist. Do not start, stop, or change the dose of Abyrone or prednisone/prednisolone without medical advice.