Description

Azataj 100mg Injection (Azacitidine) Uses, Side Effects, Dosage & Price in Pakistan

Azataj 100mg Injection (Azacitidine) is an anticancer medicine containing Azacitidine 100mg. It belongs to a group of medicines known as nucleoside metabolic inhibitors and is used in the treatment of certain blood and bone marrow disorders, including myelodysplastic syndromes (MDS) and other conditions according to the prescribing indication.

Azataj 100mg Injection is a prescription medicine and should only be given by a qualified healthcare professional. The dose and treatment schedule are decided by an oncologist or hematologist based on the patient’s condition, blood counts, and response to treatment.

What Is Azataj 100mg Injection?

Azataj 100mg Injection contains Azacitidine, a chemotherapy medicine that affects abnormal cells in the bone marrow. It is supplied as a sterile lyophilized powder that must be prepared before administration.

Azacitidine injection is available in 100mg single-dose vials and may be administered by subcutaneous injection or intravenous infusion after proper preparation.

Azacitidine is different from oral azacitidine products. Azacitidine injection should not be substituted with oral azacitidine, because the formulations have different dosing and administration schedules.

Uses of Azataj 100mg Injection

Azataj 100mg Injection may be prescribed for certain blood and bone marrow disorders, including:

• Myelodysplastic syndromes (MDS)
• Acute myeloid leukemia (AML), depending on the approved indication
• Certain related bone marrow diseases as determined by a specialist
• Conditions where abnormal bone marrow cells affect normal blood-cell production

The exact indication depends on the patient’s diagnosis and the locally approved product information. Your doctor will determine whether Azacitidine is appropriate for your condition.

How Does Azacitidine Work?

Azacitidine is a pyrimidine nucleoside analogue of cytidine. It interferes with DNA and RNA-related processes in abnormal cells.

It can affect DNA methylation and may help restore the activity of certain genes that control normal cell growth and development. This can slow the growth of abnormal bone marrow cells and may improve the production of healthy blood cells in appropriate patients.

Because azacitidine also affects normal bone marrow cells, regular blood tests and medical monitoring are important during treatment.

Azataj 100mg Injection Dosage

The dose of azacitidine is generally calculated according to the patient’s body surface area (mg/m²) rather than simply giving one 100mg vial as the complete dose.

A commonly used regimen for adults with certain indications is 75 mg/m² once daily for 7 consecutive days, followed by a treatment-free period as part of a treatment cycle. The exact regimen can vary depending on the diagnosis, blood counts, kidney function, side effects, and response to treatment.

The medicine may require more than one vial to prepare the prescribed dose.

Do not calculate or administer Azataj 100mg yourself. It must be prepared and given by trained healthcare professionals according to the prescribed regimen.

How Is Azataj 100mg Injection Given?

Azataj is supplied as a powder and must be properly reconstituted before use.

It may be administered:

• By subcutaneous injection, or
• By intravenous infusion

The healthcare professional prepares the medicine using the appropriate diluent and follows the product-specific preparation instructions.

Patients should not attempt to prepare or inject Azataj 100mg at home. Azacitidine is a cytotoxic medicine and requires appropriate handling by trained medical staff.

Side Effects of Azataj 100mg Injection

Like other chemotherapy medicines, Azacitidine may cause side effects. Common side effects may include:

• Nausea
• Vomiting
• Diarrhea or constipation
• Fatigue
• Weakness
• Loss of appetite
• Fever
• Headache
• Injection-site reactions
• Low white blood cell count
• Low platelet count
• Anemia
• Increased risk of infection

Some side effects can be related to reduced blood-cell production in the bone marrow. Therefore, regular blood tests are usually required during treatment.

Serious Side Effects

Contact your healthcare provider immediately if you experience:

• High fever or signs of infection
• Unusual bleeding or bruising
• Severe weakness
• Shortness of breath
• Persistent vomiting or diarrhea
• Severe abdominal pain
• Severe skin or allergic reactions
• Symptoms of kidney problems
• Significant changes in blood counts

Azacitidine treatment can cause neutropenia, thrombocytopenia, and anemia, which may increase the risk of infection, bleeding, or severe tiredness.

Precautions Before Using Azataj

Before treatment, tell your doctor if you:

• Have kidney disease
• Have liver problems
• Have low blood-cell counts
• Have a history of serious infections
• Have an allergy to azacitidine or any ingredient
• Are taking prescription or non-prescription medicines
• Are pregnant or planning pregnancy
• Are breastfeeding

Your doctor may perform blood tests before and during treatment to monitor your blood-cell levels and organ function.

Drug Interactions

Tell your doctor about all medicines, vitamins, and supplements you are taking.

Your healthcare professional will review your medicines to determine whether any interaction may occur or whether additional monitoring is required.

Do not start or stop another medicine without discussing it with your doctor during Azataj treatment.

Azataj 100mg During Pregnancy and Breastfeeding

Azacitidine can potentially harm an unborn baby. Women who can become pregnant should use effective contraception during treatment and for the recommended period after the final dose.

Men receiving azacitidine should also discuss appropriate contraception and reproductive precautions with their healthcare provider.

Breastfeeding should be avoided during azacitidine treatment and for the recommended period after the final dose. Current prescribing information advises avoiding breastfeeding while receiving azacitidine and for one week after the last dose.

Storage of Azataj 100mg Injection

Store Azataj according to the manufacturer’s instructions.

• Keep the unopened vial in its original packaging.
• Protect it from unsuitable temperatures and moisture.
• Keep it away from children.
• Do not use the medicine after its expiry date.
• Reconstituted and prepared medicine should be handled according to the product-specific instructions.

Because preparation and storage requirements can vary after reconstitution, healthcare professionals should follow the manufacturer’s instructions carefully.

Manufacturer of Azataj 100mg Injection

The manufacturer of Azataj 100mg Injection should be confirmed from the vial and packaging because brand availability and manufacturer information can vary by market.

Always check the original packaging for the manufacturer, batch number, expiry date, and registration information before use.

Azataj 100mg Injection Price in Pakistan

The price of Azataj 100mg Injection in Pakistan may vary depending on availability, manufacturer, supplier, import status, and current market conditions.

For the latest Azataj 100mg Injection price in Pakistan, contact Impo Medic for current availability and pricing.

Buy Azataj 100mg Injection in Pakistan

If you are looking to buy Azataj 100mg Injection (Azacitidine) in Pakistan, make sure the medicine is obtained from a reliable source and stored correctly.

Azataj is a specialist oncology medicine and should only be used with a valid prescription and under the supervision of a qualified oncologist or hematologist.

Impo Medic can help customers check the availability and current price of Azataj 100mg Injection in Pakistan.

Why Choose Impo Medic?

Impo Medic provides information and access to specialized medicines, including oncology and prescription medicines.

When purchasing Azataj 100mg Injection, always check:

• Medicine name and strength
• Manufacturer details
• Batch number
• Expiry date
• Original packaging
• Proper storage conditions
• Prescription requirements

For Azataj 100mg Injection price in Pakistan and availability, contact Impo Medic for updated information.

Frequently Asked Questions (FAQs)

What is Azataj 100mg Injection used for?

Azataj 100mg Injection contains azacitidine and is used for certain blood and bone marrow disorders, including specific types of myelodysplastic syndromes and other approved indications.

Is Azataj 100mg a chemotherapy injection?

Yes. Azacitidine is an anticancer medicine and is classified as a nucleoside metabolic inhibitor. It affects DNA and RNA processes in abnormal cells.

How is Azataj 100mg Injection administered?

Azacitidine injection can be administered by subcutaneous injection or intravenous infusion after proper preparation by healthcare professionals.

What is the usual dose of Azacitidine?

The dose is generally based on body surface area. A commonly used regimen for certain indications is 75 mg/m² once daily for 7 consecutive days, but the exact dose and schedule must be decided by the treating specialist.

Can Azataj 100mg be given at home?

Azataj should not normally be prepared or administered by patients themselves. It is a cytotoxic prescription medicine that requires appropriate preparation and administration by trained healthcare professionals.

What are the common side effects of Azataj?

Common side effects may include nausea, vomiting, fatigue, fever, diarrhea, constipation, reduced appetite, anemia, low white blood cell counts, and low platelet counts.

Can Azataj 100mg cause low blood counts?

Yes. Azacitidine can reduce blood-cell counts, including white blood cells, red blood cells, and platelets. Regular blood tests are therefore important during treatment.

Can Azataj 100mg be used during pregnancy?

Azacitidine may cause fetal harm. Women and men receiving treatment should discuss effective contraception and reproductive precautions with their healthcare provider.

Can oral azacitidine tablets replace Azataj injection?

No. Oral azacitidine and injectable azacitidine should not be substituted for one another, because their doses and treatment schedules are different.

Where can I buy Azataj 100mg Injection in Pakistan?

Azataj 100mg Injection should be purchased from a reliable medicine supplier and used under specialist medical supervision. Contact Impo Medic for current availability and price information.