Description

Abemaxen 200mg Tablet (Abemaciclib) Uses, Dosage, Side Effects & Price in Pakistan

Abemaxen 200mg Tablet (Abemaciclib) is a prescription cancer medicine used for certain types of HR-positive, HER2-negative breast cancer. It contains 200mg of abemaciclib, a targeted medicine that works by blocking CDK4 and CDK6 proteins involved in cancer-cell growth and division.

Abemaxen 200mg is manufactured by Everest Pharmaceuticals Ltd., Bangladesh. The manufacturer’s information lists Abemaxen 200 as a film-coated tablet supplied in a 60-tablet HDPE container.

What Is Abemaxen 200mg Tablet?

Abemaxen 200mg Tablet contains abemaciclib, an oral targeted anticancer medicine belonging to the CDK4/6 inhibitor class.

It is used in specific treatment plans for adults with hormone receptor-positive (HR-positive) and HER2-negative breast cancer. Depending on the cancer stage and previous treatment, abemaciclib may be prescribed alone or together with endocrine therapy such as an aromatase inhibitor, fulvestrant, or tamoxifen.

Key Product Information

Feature	Details
Brand Name	Abemaxen 200mg
Generic Name	Abemaciclib
Strength	200mg
Dosage Form	Film-coated tablet
Drug Class	CDK4/6 inhibitor
Route	Oral
Manufacturer	Everest Pharmaceuticals Ltd.
Country	Bangladesh
Pack Size	60 tablets

Abemaxen 200mg Uses

Abemaciclib is used for certain HR-positive, HER2-negative breast cancers.

Depending on the treatment plan, Abemaxen may be prescribed:

• With endocrine therapy for adults with HR-positive, HER2-negative, node-positive early breast cancer at high risk of recurrence.
• With an aromatase inhibitor as initial endocrine-based treatment for advanced or metastatic breast cancer.
• With fulvestrant when advanced or metastatic breast cancer has progressed after endocrine therapy.
• As monotherapy for certain adults with advanced or metastatic HR-positive, HER2-negative breast cancer following endocrine therapy and previous chemotherapy in the metastatic setting.

The appropriate treatment depends on factors such as cancer type, stage, hormone receptor status, HER2 status and previous treatment.

How Does Abemaciclib Work?

Abemaciclib works by inhibiting cyclin-dependent kinases 4 and 6 (CDK4 and CDK6).

These proteins help regulate the cell cycle and allow cells to progress toward division. By blocking CDK4 and CDK6, abemaciclib can slow the growth and multiplication of certain cancer cells. This is why it is considered a targeted cancer therapy.

Abemaxen 200mg Dosage

The recommended dose depends on how abemaciclib is being used.

When abemaciclib is used as monotherapy, the recommended starting dose in the current U.S. prescribing information is 200mg twice daily. When used in combination with fulvestrant, tamoxifen or an aromatase inhibitor, the recommended starting dose is generally 150mg twice daily.

Therefore, the 200mg strength is particularly relevant to treatment regimens where abemaciclib is prescribed as monotherapy.

Treatment may be interrupted or the dose reduced if significant side effects occur. Patients with certain liver problems or those taking interacting medicines may also require dosage adjustments.

Do not change the dose of Abemaxen 200mg or stop treatment without your oncologist’s advice.

How to Take Abemaxen 200mg Tablet

Take Abemaxen exactly as prescribed by your doctor.

• Take the tablet orally with or without food.
• Take it at approximately the same times every day.
• Swallow the tablet whole.
• Do not chew, crush or split the tablet.
• If you miss a dose or vomit after taking it, take the next dose at its usual scheduled time.
• Do not take two doses together to make up for a missed dose.

Your oncologist may change the treatment schedule depending on your response and side effects.

Abemaxen 200mg Side Effects

Like other cancer medicines, Abemaxen 200mg can cause side effects. Commonly reported adverse reactions with abemaciclib include:

• Diarrhea
• Neutropenia
• Nausea
• Abdominal pain
• Infections
• Fatigue
• Anemia
• Decreased appetite
• Vomiting
• Headache
• Hair loss
• Low white blood cell counts
• Low platelet counts

Diarrhea is particularly common during abemaciclib treatment and may occur early after starting therapy. Prompt medical advice is important if diarrhea becomes severe or persistent.

Serious Side Effects

Abemaciclib may also cause serious reactions, including:

• Severe diarrhea and dehydration
• Neutropenia and other blood-cell abnormalities
• Serious infections
• Liver problems
• Interstitial lung disease or pneumonitis
• Blood clots, including deep-vein thrombosis and pulmonary embolism

Seek medical attention if you experience severe breathing problems, chest pain, persistent fever, unusual bleeding or other serious symptoms.

Abemaxen 200mg Tablet Precautions

Before starting treatment, tell your doctor if you have:

• Liver disease
• Previous blood-clotting problems
• Low blood-cell counts
• Lung or breathing problems
• Recurrent infections
• Other medical conditions
• A history of medicine allergies

Regular monitoring may include complete blood counts and liver-function tests during treatment. Your doctor may also monitor you for diarrhea, infection, blood clots and respiratory symptoms.

Abemaxen 200mg Tablet Drug Interactions

Abemaciclib is mainly metabolized through the CYP3A pathway. Some medicines can therefore increase or decrease the amount of abemaciclib in the body.

Strong CYP3A inhibitors may require an abemaciclib dose reduction, while strong or moderate CYP3A inducers should generally be avoided because they can reduce abemaciclib exposure. Grapefruit and grapefruit products should also be avoided during treatment.

Tell your doctor about all prescription medicines, over-the-counter medicines, vitamins and supplements before starting Abemaxen.

Abemaxen 200mg During Pregnancy and Breastfeeding

Abemaciclib may cause fetal harm. Women who can become pregnant should discuss effective contraception with their healthcare professional before and during treatment.

The manufacturer’s information recommends effective contraception during treatment and for 3 weeks after the last dose. Animal studies also suggest that abemaciclib may affect male fertility.

Breastfeeding should be discussed with a healthcare professional before starting treatment.

Abemaxen 200mg Storage

Store Abemaxen below 30°C in a cool, dry place and protect it from light. Keep the medicine out of the reach of children.

Keep the tablets in their original container until they are needed.

Abemaxen 200mg Manufacturer

Abemaxen 200mg Tablet is manufactured by Everest Pharmaceuticals Ltd., Bangladesh. The manufacturer’s product information lists Abemaxen 200 as containing 200mg of abemaciclib and supplied in a 60-tablet HDPE container.

Everest Pharmaceuticals also lists Abemaxen 200 among its oncology products.

Abemaxen 200mg Price in Pakistan

The Abemaxen 200mg Tablet price in Pakistan can vary depending on imported stock, supplier, pack size and market conditions.

Because this is a prescription oncology medicine, customers should confirm the latest price and availability before placing an order.

For current availability and pricing, check the product listing at Impo Medic.

Buy Abemaxen 200mg Tablet in Pakistan

If you are looking for Abemaxen 200mg Tablet in Pakistan, Impo Medic provides online access to imported medicines, subject to product availability.

Abemaxen 200mg is a prescription cancer medicine and should be used only according to the treatment plan provided by a qualified oncologist.

Before ordering, confirm the product name, strength, pack size, current price and availability.

Why Choose Impo Medic?

• Easy access to medicine information
• Online ordering convenience
• Updated product availability
• Clear pricing information
• Access to imported medicines where available
• Customer support for product-related queries
• Responsible approach to prescription medicines

FAQs About Abemaxen 200mg Tablet (Abemaciclib)

What is Abemaxen 200mg Tablet used for?

Abemaxen 200mg contains abemaciclib and is used in specific treatment plans for HR-positive, HER2-negative breast cancer, including certain advanced and metastatic cases.

What is the active ingredient in Abemaxen 200mg?

The active ingredient is abemaciclib, a targeted CDK4/6 inhibitor.

What is the usual Abemaxen 200mg dosage?

When abemaciclib is used as monotherapy, the recommended starting dose is 200mg twice daily. The actual treatment plan must be determined by the treating oncologist.

Can Abemaxen 200mg be taken with food?

Yes. Abemaciclib tablets can generally be taken with or without food.

What are the common side effects of Abemaxen 200mg?

Common side effects include diarrhea, nausea, neutropenia, fatigue, infections, anemia, abdominal pain, vomiting, headache and decreased appetite.

Can Abemaxen cause diarrhea?

Yes. Diarrhea is one of the most common side effects of abemaciclib. Severe or persistent diarrhea should be reported to a healthcare professional.

Can Abemaxen 200mg interact with other medicines?

Yes. Medicines that affect the CYP3A pathway can change abemaciclib levels. Grapefruit products should also be avoided. Always inform your doctor about all medicines and supplements you use.

Is Abemaxen 200mg available in Pakistan?

Availability can change according to imported stock and supplier conditions. Check the current Impo Medic listing for availability and pricing.

Legal & Medical Disclaimer

This article is for general educational purposes only and does not replace professional medical advice. Abemaxen 200mg is a prescription oncology medicine and should be used under the supervision of a qualified oncologist. Dosage, treatment duration and combinations with other medicines must be determined according to the patient’s condition and official prescribing information.