Description

Xolair Injection 150mg (Omalizumab) – Uses, Dosage, Side Effects & Price in Pakistan

Xolair Injection 150mg (Omalizumab) is a prescription biological medicine used as an add-on treatment for certain allergic and inflammatory conditions. It contains omalizumab, a monoclonal antibody that targets immunoglobulin E (IgE), an antibody involved in allergic reactions. Xolair is available as a 150mg solution for injection in a pre-filled syringe or pre-filled pen, depending on the market and product presentation.

Xolair treatment should be started by a doctor experienced in treating the condition for which it is prescribed. The dose and treatment schedule depend on the patient’s condition and, for some indications, factors such as body weight and blood IgE levels.

What Is Xolair Injection 150mg?

Xolair 150mg contains 150mg of omalizumab in 1mL of solution in the pre-filled syringe or pen presentation. Omalizumab is a humanised monoclonal antibody produced using recombinant DNA technology.

Unlike conventional medicines that directly relieve symptoms, omalizumab works by targeting IgE. By binding to free IgE in the body, it reduces the amount of IgE available to trigger allergic reactions and related inflammation.

Xolair 150mg Uses

The approved Xolair 150mg Uses depend on the patient’s age, condition and treatment history.

Xolair is used as an add-on treatment for severe persistent allergic asthma in appropriate patients. In adults and adolescents, it is intended for patients with convincing IgE-mediated allergic asthma who have ongoing symptoms or severe exacerbations despite appropriate high-dose inhaled corticosteroid and long-acting beta2-agonist treatment.

Xolair is also approved for:

• Chronic spontaneous urticaria (CSU) in adults and adolescents aged 12 years and above when H1 antihistamine treatment does not provide adequate control.
• Severe chronic rhinosinusitis with nasal polyps (CRSwNP) in adults when intranasal corticosteroids do not provide sufficient control.

Xolair is not a general treatment for every type of asthma, allergy or skin rash. A doctor must determine whether the patient’s condition matches the approved use of omalizumab.

How Does Omalizumab Work?

Omalizumab works by targeting IgE, which plays an important role in allergic reactions.

After binding to free IgE in the blood, omalizumab reduces the amount of IgE available to interact with allergy-related cells. This can reduce allergic inflammation and help improve symptoms in suitable patients with allergic asthma. Its effect on IgE-related pathways also contributes to its use in conditions such as chronic spontaneous urticaria and nasal polyps.

Because Xolair changes part of the immune response, patients should continue following their doctor’s overall treatment plan and should not stop other prescribed medicines unless instructed.

Xolair 150mg Dosage

There is no single standard dose for every patient. For allergic asthma and chronic rhinosinusitis with nasal polyps, the Xolair dose is determined using the patient’s body weight and blood IgE level. The medicine may be administered every 2 or 4 weeks depending on the calculated dose and treatment plan.

For chronic spontaneous urticaria, the recommended dose is generally 300mg every 4 weeks for adults and adolescents aged 12 years and above. Therefore, a 150mg presentation may be used as part of the prescribed dose rather than representing the complete treatment dose.

Patients should never change the dose or injection frequency themselves. The doctor will determine the appropriate schedule based on the indication and individual response.

How Is Xolair 150mg Given?

Xolair is administered by subcutaneous injection, meaning it is injected under the skin. Depending on the product presentation and the patient’s risk of severe allergic reactions, administration may be performed by a healthcare professional or, after appropriate training, by the patient or caregiver.

The first doses require particular attention because Xolair can rarely cause a serious allergic reaction called anaphylaxis. Patients should follow their healthcare professional’s instructions regarding observation and administration.

Xolair should not be used to treat an acute asthma attack. A fast-acting rescue medicine should be used for sudden breathing problems according to the patient’s asthma action plan.

Xolair 150mg Side Effects

Like all medicines, Xolair may cause side effects. Possible Xolair 150mg side effects include:

• Headache
• Injection-site pain, swelling, redness or itching
• Joint pain
• Dizziness
• Upper respiratory tract infections
• Sinusitis
• Abdominal discomfort in some patients

The exact side effects can vary depending on the condition being treated and the patient’s age.

Serious Allergic Reaction

A serious allergic reaction, including anaphylaxis, is an important safety concern with omalizumab. It can occur after an injection and may include difficulty breathing, swelling of the throat or tongue, dizziness, fainting or widespread hives.

Seek urgent medical attention if symptoms suggesting a severe allergic reaction occur after receiving Xolair.

Xolair Precautions

Tell your doctor before using Xolair if you have previously experienced a severe allergic reaction to omalizumab or any of its ingredients.

Xolair is not intended to treat an acute asthma attack, and patients with asthma should continue their prescribed rescue and controller medicines unless their doctor changes the treatment plan.

Patients should also tell their doctor about other medicines and medical conditions before starting treatment.

Xolair does not directly eliminate every possible cause of allergic symptoms, so regular medical follow-up is important to assess whether treatment is providing the desired benefit.

Xolair 150mg Storage

Xolair should generally be stored in a refrigerator at 2°C to 8°C and protected from light. It should not be frozen. The medicine should be kept in its original packaging until it is needed.

Because Xolair is a biological medicine, proper storage and handling are particularly important. When purchasing an imported product, customers should check that the packaging is intact and that appropriate storage conditions have been maintained.

Xolair Manufacturer

Xolair is associated with Novartis, and the EMA lists Novartis Europharm Limited as the marketing authorisation holder for Xolair in the European Union.

The actual manufacturer or manufacturing site may vary by product presentation and market. Customers should therefore check the physical packaging for the manufacturer, batch number, expiry date and other product details before purchase. (EMA)

Xolair 150mg Price in Pakistan

The Xolair 150mg Price in Pakistan can vary depending on supplier, import costs, availability, product presentation and current stock. Imported biological medicines may have changing prices because of their specialist handling and supply requirements.

Before ordering, confirm the exact 150mg strength, formulation, manufacturer, expiry date and packaging condition.

Buy Xolair 150mg Injection in Pakistan

If you are looking to Buy Xolair 150mg Injection in Pakistan, contact a reliable medicine supplier to check current availability, price and delivery options.

Because Xolair is a prescription biological medicine, it should only be used according to a qualified healthcare professional’s treatment plan. Customers should also confirm the product’s storage condition and packaging before accepting an order.

For patients already prescribed omalizumab, the correct dose and injection schedule should always be followed as advised by the treating doctor.

Why Choose ImpoMedic?

ImpoMedic helps customers find specialized and imported medicines with clear product information and order support. If you want to buy Xolair 150mg in Pakistan, you can contact ImpoMedic to check the latest price, availability and delivery options.

For a biological medicine like Xolair, customers can also confirm important details such as the 150mg strength, manufacturer, batch number, expiry date and storage condition before ordering.

FAQs About Xolair Injection 150mg (Omalizumab)

1. What is Xolair Injection 150mg used for?

Xolair contains omalizumab and is used as an add-on treatment for certain patients with severe allergic asthma, chronic spontaneous urticaria and severe chronic rhinosinusitis with nasal polyps.

2. What is the active ingredient in Xolair 150mg?

The active ingredient is omalizumab. Each 150mg pre-filled syringe or pen contains 150mg of omalizumab in 1mL.

3. How is Xolair 150mg given?

Xolair is administered by subcutaneous injection. Depending on the product presentation and patient’s circumstances, it may be given by a healthcare professional or by a trained patient/caregiver.

4. What are the common Xolair 150mg side effects?

Possible side effects include headache, injection-site reactions, joint pain, sinusitis and upper respiratory tract infections.

5. Can Xolair cause an allergic reaction?

Yes. Xolair can rarely cause anaphylaxis, a serious allergic reaction. Seek urgent medical attention if breathing difficulty, swelling, fainting or other severe allergic symptoms occur after an injection.

6. Is Xolair 150mg the complete dose for every patient?

No. The required dose and injection frequency depend on the condition being treated. For allergic asthma and nasal polyps, dosing is based on factors including body weight and blood IgE levels.

7. What is the Xolair 150mg Price in Pakistan?

The price can vary depending on supplier, availability, imported stock and product presentation. Contact ImpoMedic for the current price and availability.

8. Can I Buy Xolair 150mg Injection in Pakistan?

You can contact ImpoMedic to check current availability, price and delivery options. Xolair is a prescription biological medicine and should be used according to a qualified healthcare professional’s treatment plan.

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